Reviews
14 February 2025
Vol. 42 No. 2 (2020)
PAIN DIAGNOSIS AND TREATMENT ACCORDING TO THE PAIN GENERATING FACTORS
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Chronic pain impacts on many aspects of patient life affecting autonomy, sleep, social activities and also employment. Adequate pain control is often challenging in patients with chronic pain, despite the availability of many medications and interventional techniques. Limitations to successful pain treatment are the poor understanding of contributing mechanisms and the lack of a mechanism based approach in clinical practice.
The purpose of this article is to identify the factors contributing to pain generation in order to guide a personalized treatment. We analyze tissue specificity for chemical and physical stresses potentially causing pain, the changes that occur in the peripheral and central pain pathways during disease, the stimuli that, acting on a pathological pain pathway, can trigger pain. The pain generating factors should be recognized in each patient and addressed with pharmacological, rehabilitation and invasive interventions.
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PAIN DIAGNOSIS AND TREATMENT ACCORDING TO THE PAIN GENERATING FACTORS. (2025). Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 42(2), 124-132. https://doi.org/10.4081/gimle.449
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