ATTI 80° CONGRESSO NAZIONALE SIML
3 March 2025
Vol. 39 No. 3 (2017)
[Allergens in occupational allergy: risk management]
Gli allergeni nell’allergia occupazionale: management del rischio
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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The first essential aspect for the prevention of occupational allergy is related to the accurate allergen identification and characterization. At present many efforts are made to characterize the potential for a chemical to be a sensitizing agent. 'Omics' show great promise to identify key cellular and molecular events relevant to development of an adverse outcome pathway for respiratory sensitizers. One approach that shows promise is based on the measurement of the peptide reactivity of chemicals; the potential to form stable associations with protein/peptide being a key requirement for the induction of sensitization. Sensitization is a dose-related phenomenon, therefore the lower the exposure the lower the risk of sensitization. In any way, establishing occupational exposure limits for chemical allergens presents numerous difficulties. Therefore it is important using alternative exposure recommendations and risk management practices, including medical surveillance and tertiary prevention, to aid in protecting workers from exposures to allergens.
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How to Cite
[Allergens in occupational allergy: risk management]: Gli allergeni nell’allergia occupazionale: management del rischio. (2025). Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 39(3), 172-174. https://doi.org/10.4081/gimle.625
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