ATTI 80° CONGRESSO NAZIONALE SIML
3 March 2025
Vol. 39 No. 3 (2017)
https://doi.org/10.4081/gimle.627

[Diagnostic approach to work-related allergic respiratory diseases]

Approccio diagnostico alle patologie respiratorie allergiche professionali

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Gabriella Guarnieri
gabriella.guarnieri@unipd.it
Medicina del Lavoro, Fisiopatologia Respiratoria, Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari, Azienda Ospedaliera e Università di Padova, Italy.

An accurate diagnosis of occupational allergic respiratory diseases is crucial because they are related to disability, loss of work and worsening of psychosocial and economic status of workers. Early diagnosis is therefore essential to prevent the progression of allergic respiratory diseases and to implement preventive measures. The most frequent occupational allergic respiratory diseases are asthma (OA) and rhinitis (OR), less frequently hypersensitivity pneumonia (HP) and non-asthmatic eosinophilic bronchitis (NAEB). The diagnosis is based on the objective evidence of the disease, on a clear correlation with the work activity and the identification of a specific sensitizing agent in the workplace. Reference standard methods are available, such as Specific Inhalation Challenge in the laboratory or in the workplace. A multidisciplinary approach in highly-specialized centres is always recommended for diagnostic confirmation, as it is accompanied by greater diagnostic sensitivity and specificity.

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1) Malo JL, Tarlo SM, Sastre J, et al. An official American Thoracic Society Workshop Report: presentations and discussion of the fifth Jack Pepys Workshop on Asthma in the Workplace. Comparisons between asthma in the workplace and non-work-related asthma. Ann Am Thorac Soc 2015; 12(7): S99-S110. DOI: https://doi.org/10.1513/AnnalsATS.201505-281ST
2) Moscato G, Vandenplas O, Van WijK RG, et al. EAACI position paper on occupational rhinitis. Respir Res 2009; 3: 10-16. DOI: https://doi.org/10.1186/1465-9921-10-16
3) Quirce S, Vandenplas O, Campo M, et al. Occupational hypersensitivity pneumonitis: an EAACI position paper. Allergy 2016; 71(6): 765-79. DOI: https://doi.org/10.1111/all.12866
4) Baur X, Sigsgaard T, Aasen TB, et al. ERS Task Force on the Management of Work-related Asthma. Guidelines for the management of work-related asthma. Eur Respir J 2012; 39: 529-45. DOI: https://doi.org/10.1183/09031936.00096111
5) Vandenplas O, Suojalehto H, Cullinan P. Diagnosing occupational asthma. Clin Exp Allergy 2017; 47(1): 6-18 6) Ferrazzoni S, Scarpa MC, Guarnieri G, et al. Exhaled nitric oxide and breath condensate ph in asthmatic reactions induced by isocyanates. Chest 2009; 136(1): 155-162. DOI: https://doi.org/10.1378/chest.08-2338
7) Munoz X, Cruz MJ, Bustamante V et al. Work-related asthma: diagnosis and prognosis of immunological occupational asthma and work-exacerbated asthma. J Investig Allergol Clin Immunol 2014; 24(6): 396-405.
8) Vandenplas O, Suojalehto H, Aasen TB, et al. ERS Task Force on Specific Inhalation Challenges with Occupational Agents Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement Eur Respir J 2014; 43(6): 1573-87. DOI: https://doi.org/10.1183/09031936.00180313
9) Ottaviano G, Fokkens WJ. Measurements of nasal airflow and patency: a critical review with emphasis on the use of peak nasal inspiratory flow in daily practice. Allergy 2016; 71: 162-74. DOI: https://doi.org/10.1111/all.12778
10) Dordal MT, Lluch-Bernal M, Sanchez MC et al. Allergen-specific nasal provocation testing: review by Rhinoconjunctivitis Committee of Spanish Society of Allergy and Clinical Immunology. J Investig Allergol Clin Immunol 2011; 21(1): 1-12.
11) Moscato G, Pala G, Cullinan P, et al. EAACI Position Paper on assessment of cough in the workplace. Allergy 2014; 69: 292-304. DOI: https://doi.org/10.1111/all.12352
12) Wiggans RE, barber CM. Metalworking fluids: a new cause of occupational non-asthmatic eosinophilic bronchitis. Thorax 2017; 72.579-580. 13) Thomeer MJ, Costabe U, Rizzato G, et al. Comparison of registries of interstitial lung diseases in three European countries. Eur Respir J Suppl 2001; 32: 114s-118s. DOI: https://doi.org/10.1136/thoraxjnl-2016-208827
14) Lacasse Y, Selman M, Castabel U, et al. Clinical diagnosis for hypersensitivity pneumonitis. Am J Respir Crit Care Med 2003; 168: 952-958. 15) Yoshizawa Y, Ohtani Y, Hayakawa H, et al. Chronic hypersensitivity pneumonitis in Japan: a nationalwide epidemiologic survey. J Allergy Clin Immunol 1999; 103: 315-320. DOI: https://doi.org/10.1016/S0091-6749(99)70507-5

How to Cite



[Diagnostic approach to work-related allergic respiratory diseases]: Approccio diagnostico alle patologie respiratorie allergiche professionali. (2025). Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 39(3), 178-181. https://doi.org/10.4081/gimle.627
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